منابع مشابه
Leukocyte Locomotion and Chemotaxis
Polymorphonuclear leukocyte (PMN) locomotion and chemotaxis have been evaluated by direct microscopic observation of individual cells in thin slide-cover slip preparations, and also by observations on populations of cells migrating into a Millipore filter. The direct microscopic method used the polarity of the locomoting PMNs (broad, advancing lamellipodium and knoblike constriction at the rear...
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Human polymorphonuclear leukocytes (PMN) migrate into tissues in response to chemoattractants, yet it is not known whether this process alters the functional capabilities of the PMN. Using recombinant human interleukin-8 (rHIL-8, 100 ng/ml) as a stimulus, we compared a population of PMN that migrated through a polyvinylpyrrolidone-coated polycarbonate filter containing 8.0 microns diameter pore...
متن کاملIntravascular Leukocyte Chemotaxis: The Rules of Attraction
The security system of the body against pathogenic invaders includes leukocytes that efficiently scan the organism. Leukocytes within the vasculature utilize the comprehensive circulatory system to examine the blood vessels of the entire body for signs of e.g. bacteria displayed on vascular endothelial cells. Upon infection, a successful immune response is dependent on prompt recruitment of leu...
متن کاملSignal-activated phospholipase regulation of leukocyte chemotaxis.
Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated. A critical step in inflammation is the attraction of leukocytes to injured or diseased tissue. Chemotaxis of leukocytes, a requisite process for monocyte and neutrophil extravasation from ...
متن کاملDefective Mononuclear Leukocyte Chemotaxis in the Chediak
Chemotaxis of mononuclear leukocytes from humans, mink, and cattle was evaluated in vitro using a morphologic Boyden chamber technique and a new labeled mononuclear radioassay with a double micropore filter system. Significantly decreased mononuclear leukocyte chemotactic responses were noted when human, mink, or cattle Chediak-Higashi cells were tested using autologous serum or endotoxin-activ...
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ژورنال
عنوان ژورنال: Journal of the Islamic Medical Association of North America
سال: 1982
ISSN: 2160-9829,0899-8299
DOI: 10.5915/14-3-12185